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Alder-ene reaction: aromaticity and activation-strain analysis.

Israel Fernández1, F Matthias Bickelhaupt

  • 1Departamento de Química Orgánica, Facultad de Química, Universidad Complutense, Madrid 28040, Spain. israel@quim.ucm.es

Journal of Computational Chemistry
|December 7, 2011
PubMed
Summary

This study computationally explores Alder-ene reaction trends. Reactivity barriers decrease when third-period atoms like sulfur or phosphorus are in the enophile, impacting reaction pathways.

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