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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
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Pharmacological management
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
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Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents01:29

Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel Disease...
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Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide generation. 

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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
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Published on: February 6, 2019

Radiation proctitis: current strategies in management.

Nhue L Do1, Deborah Nagle, Vitaliy Y Poylin

  • 1Division of Colon and Rectal Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School Boston, 330 Brookline Avenue, Stoneman 9, Boston, MA 02215, USA.

Gastroenterology Research and Practice
|December 7, 2011
PubMed
Summary

Radiation proctitis, a complication of pelvic radiation therapy, is usually managed without surgery. This review focuses on current non-surgical treatment options for radiation proctitis.

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Last Updated: May 26, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
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Area of Science:

  • Gastroenterology
  • Oncology
  • Radiation Oncology

Background:

  • Radiation proctitis is a common complication after pelvic radiation therapy for cancers.
  • It significantly impacts patient quality of life.

Purpose of the Study:

  • To review and summarize current non-surgical treatment modalities for radiation proctitis.

Main Methods:

  • Literature review of current treatment options for radiation proctitis.
  • Focus on nonsurgical management strategies.

Main Results:

  • Nonsurgical treatments are the mainstay for radiation proctitis.
  • Various endoscopic and medical therapies are available.

Conclusions:

  • Effective management of radiation proctitis relies on understanding available nonsurgical treatments.
  • Timely intervention can improve patient outcomes.