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Related Concept Videos

Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
Gene Therapy00:59

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be inserted. The...
What is Genetic Engineering?00:49

What is Genetic Engineering?

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Related Experiment Video

Updated: May 26, 2026

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood
09:29

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

Published on: February 1, 2013

[Genetic safety of cellular therapy].

N P Bochkov, E S Voronina, L D Katosova

    Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
    |December 8, 2011
    PubMed
    Summary

    Mesenchymal stem cell cultures exhibit significant genome instability, including DNA damage and aneuploidy, even at early passages. Cytogenetic monitoring is crucial for ensuring the safety of stem cell therapies.

    Area of Science:

    • Genetics
    • Cell Biology
    • Regenerative Medicine

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