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Updated: May 26, 2026

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood
09:29

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

Published on: February 1, 2013

[Genetic safety of cellular therapy]

N P Bochkov, E S Voronina, L D Katosova

    Vestnik Rossiiskoi Akademii Meditsinskikh Nauk
    |December 8, 2011
    PubMed
    Summary

    Mesenchymal stem cell cultures exhibit significant genome instability, including DNA damage and aneuploidy, even at early passages. Cytogenetic monitoring is crucial for ensuring the safety of stem cell therapies.

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