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Updated: May 26, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
The association between morning cortisol and adiposity in children varies by weight status
Emily E Hill1, Joey C Eisenmann, Douglas Gentile
1Department of Kinesiology, Michigan State University, East Lansing, MI, USA.
Insights
Morning cortisol levels showed a positive association with changes in waist circumference among overweight children over nine months. This suggests a potential link between stress hormones and adiposity progression in this group.
Area of Science:
- Pediatric endocrinology
- Childhood obesity research
- Stress physiology
Background:
- Childhood obesity is a growing public health concern.
- Cortisol, a stress hormone, has been implicated in metabolic regulation.
- Understanding the relationship between cortisol and adiposity in children is crucial for developing effective interventions.
Purpose of the Study:
- To investigate the association between morning salivary cortisol levels and measures of adiposity (BMI and waist circumference) in children.
- To examine these associations at baseline and after a 9-month follow-up period.
Main Methods:
- Cross-sectional and longitudinal analyses were performed on data from 649 children (aged 9.6 years) at baseline and 316 children at follow-up.
- Adiposity was assessed using Body Mass Index (BMI) and waist circumference (WC).
- Morning salivary cortisol levels were measured from single samples.
Main Results:
- No significant correlations were observed between baseline cortisol and BMI or WC in the overall cohort.
- Baseline cortisol did not predict changes in BMI z-score or WC over the 9-month follow-up.
- However, among overweight children, baseline cortisol was significantly associated with increases in WC and BMI z-score over the follow-up period.
Conclusions:
- Morning cortisol levels are positively related to increases in waist circumference over nine months in overweight children.
- Further research is recommended to explore the association between 24-hour cortisol patterns and direct measures of trunk fat in pediatric populations.
Objective:
To examine the associations between morning cortisol and adiposity in children at baseline and 9-month follow-up.
Methods:
Participants included 649 (301 males, 348 females) children (9.6 +/- 0.9 years) for the cross-sectional analysis and 316 (153 males, 163 females) for the longitudinal analysis. Body mass index (BMI, kg/m2) was calculated from measured height and weight and waist circumference (WC, cm) was measured at the superior border of the iliac crest. Cortisol was assessed via saliva samples collected on a single morning. Cross-sectional and longitudinal analyses were conducted to examine the relationships between cortisol and adiposity.
Results:
Approximately 31% were overweight (17.7%) or obese (12.8%). The mean cortisol level was 9.36 +/- 5.64 nmol/L (0.34 +/- 0.20 microg/dL). At baseline, no significant correlations were found between cortisol and BMI or WC (r < 0.07). Baseline cortisol did not correlate with change in BMI z-score (r = -0.03) or WC (r < -0.01) over the follow-up period. When examined by weight status, baseline cortisol was significantly related to changes in WC (r = 0.32) and BMI z-score (r = 0.28) among overweight subjects.
Conclusions:
A positive relationship was found between morning cortisol and change in WC over 9 months in overweight children. Future studies should examine the association between 24-h cortisol patterns and direct measures of trunk fat.
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