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Updated: May 26, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
Published on: September 12, 2011
Decreased activation and increased lateralization in brain functioning for selective attention and response
Xiawei Ou1, Jeffrey H Snow, Amy K Byerley
1Department of Radiology, Arkansas Children's Hospital, Little Rock, USA. ouxiawei@uams.edu
Abstract:
We used functional magnetic resonance imaging to evaluate functional activity in the brain of adolescents with spina bifida when performing selective attention and response inhibition tasks. We then compared the results to that of age-matched controls. Our results showed that adolescents with spina bifida had decreased frontal and superior parietal activation and more apparently low involvement of left brain hemisphere during these tasks. Our results indicated activation deficits and possibly abnormal functional organization in adolescents with spina bifida and associated pathologies such as hydrocephalus.
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