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Published on: April 28, 2015
Amine-functionalized lanthanide-doped KGdF4 nanocrystals as potential optical/magnetic multimodal bioprobes
Qiang Ju1, Datao Tu, Yongsheng Liu
1Key Laboratory of Optoelectronic Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
Abstract:
Amine-functionalized lanthanide-doped KGdF(4) nanocrystals, synthesized via a facile one-step solvothermal route by employing polyethylenimine as the surfactant and capping ligand, have been demonstrated to be sensitive time-resolved FRET bioprobes to detect a trace amount of biomolecules such as avidin at a concentration of 5.5 nM and to be potential T(1)-MRI contrast agents due to a large longitudinal relaxivity of Gd(3+) (5.86 S(-1)·mM(-1) per Gd ion and 3.99 × 10(5) S(-1)·mM(-1) per nanocrystal).
