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Updated: May 26, 2026

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation
Published on: August 1, 2010
A case of retroperitoneal immature teratoma with nephroblastic components
Mitsuaki Ishida1, Machiko Hotta, Motoki Ohta
1Department of Clinical Laboratory Medicine, Division of Diagnostic Pathology. Shiga University of Medical Science, Shiga, Japan. mitsuaki@belle.shiga-med.ac
Abstract:
The presence of nephroblastic components is extremely rare in retroperitoneal teratomas. We described an unusual case of right retroperitoneal immature teratoma with nephroblastic components in a 2-month-old Japanese girl. Approximately 15% of tumor was composed of nephroblastic components within immature teratoma components. Although overlap of histopathological findings between teratomas with nephroblastic components and teratoid Wilms tumors, which have heterologous elements in >50% of the tumor, occasionally exist, the most distinct feature of teratoma is the presence of organoid arrangement. The prognosis of retroperitoneal teratomas with nephroblastic components has not yet been established, therefore, additional case studies are needed.
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