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Updated: May 26, 2026

Hyperglycemic Clamp and Hypoglycemic Clamp in Conscious Mice
Published on: January 26, 2024
A rare cause of hypoglycaemia
Pinaki Dutta1, Anil Bhansali, Santosh Kumar
1PGIMER, Endocrinology, Sector 12, Chandigarh, 160012, India.
Abstract:
We describe the case of a 77-year-old man who was admitted with recurrent episodes of altered behaviour. These episodes were related to insulin-like growth factor II (IGF-II) mediated hypoglycaemia. Imaging revealed a large retroperitoneal mass and he underwent debulking surgery uneventfully. Histopathology revealed a solitary fibroma with intense immunostaining positive for CD34 and vimentin, suggesting a mesenchymal origin of the tumour. Later he received chemo/radiotherapy and is on prednisolone with abatement of hypoglycaemic episodes.
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