Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Lidocaine in the middle ear.

D F Wilson¹, R S Hodgson

¹Ear Medical Group, Portland, Ore 97209.

The Laryngoscope

|October 1, 1990

Summary

Lidocaine hydrochloride used for ear canal anesthesia was detected in middle ear fluid during tympanotomy. This challenges the use of clear middle ear fluid alone to identify perilymph or cerebrospinal fluid.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hospital Clinics: Service of Prof. Donald Maclean, Medical College of University, Michigan.

The Dental register·2021

Same author

A non-randomised single centre cohort study, comparing standard and modified bowel preparations, in adults with cystic fibrosis requiring colonoscopy.

BMC gastroenterology·2019

Same author

Geriatric dentistry, teaching and future directions.

Australian dental journal·2015

Same author

Malnutrition: why should we care?

Internal medicine journal·2013

Same author

Quantitative assessment of brain microvascular and tissue oxygenation during cardiac arrest and resuscitation in pigs.

Anaesthesia·2013

Same author

Human papillomavirus and oral disease - emerging evidence: a review.

Australian dental journal·2013

Area of Science:

Otolaryngology
Anesthesiology
Surgical Research

Background:

Local anesthesia for ear canal procedures often involves lidocaine hydrochloride injections.
Accidental or intentional entry into the middle ear space can occur during otologic surgery.
Distinguishing middle ear effusions from perilymph or cerebrospinal fluid (CSF) is critical for surgical management.

Purpose of the Study:

To investigate the presence and concentration of lidocaine in middle ear fluid following external ear canal anesthesia.
To evaluate the reliability of detecting clear middle ear fluid as an indicator of perilymph or CSF.

Main Methods:

Lidocaine hydrochloride was administered for external ear canal anesthesia prior to tympanotomy.
Middle ear fluid was collected during tympanotomy in fifteen surgical cases.
Fluid samples were analyzed using enzyme immunoassay to quantify lidocaine levels.

Main Results:

Lidocaine was detected in the middle ear fluid of all cases where sufficient fluid volume was available for collection.
The presence of lidocaine was confirmed even in surgeries not typically associated with perilymphatic fluid, such as tympanotomy for otosclerosis.
Quantification revealed varying percentages of lidocaine in the collected middle ear fluid.

Conclusions:

The presence of lidocaine in middle ear fluid following external ear canal anesthesia is common.
Relying solely on the presence of clear middle ear fluid, even if reaccumulating, is insufficient for definitively identifying perilymph or CSF.
Further diagnostic methods are necessary to accurately differentiate middle ear fluids in the context of otologic surgery and anesthesia.

Related Experiment Videos