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A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis

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Published on: May 10, 2022

Night eating syndrome: an overview.

Walter Milano¹, Michele De Rosa, Luca Milano

¹Mental Health Unit, Distretto 24, ASL Napoli 1 Centro, Naples, Italy.

The Journal of Pharmacy and Pharmacology

|December 14, 2011

Summary

Night Eating Syndrome (NES) involves disrupted eating patterns and circadian rhythms, often linked to obesity. Selective serotonin reuptake inhibitors (SSRIs) show promise in improving NES symptoms.

Area of Science:

Behavioral Science
Neuroendocrinology
Clinical Psychology

Background:

Night Eating Syndrome (NES) is a distinct disorder characterized by specific eating patterns and circadian disruptions.
NES is frequently comorbid with obesity and mood disorders, highlighting its clinical significance.
Current understanding of NES pathogenesis is evolving, with abnormal neuroendocrine factors implicated.

Purpose of the Study:

To review the diagnostic criteria and nosographic features of Night Eating Syndrome (NES).
To explore the leading ethiopathogenetic theories for NES based on current scientific literature.
To discuss potential therapeutic interventions for NES.

Main Methods:

Literature review of recent evidence on NES.

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Analysis of diagnostic characteristics and ethiopathogenetic theories.

Evaluation of therapeutic options, including pharmacological and non-pharmacological approaches.

Main Results:

NES is defined by reduced daytime intake, evening hyperphagia, nocturnal awakenings with food consumption, and altered circadian rhythms.
Selective serotonin reuptake inhibitors (SSRIs) demonstrate efficacy by modulating serotonin transporter activity and improving clinical symptoms.
NES is significantly associated with obesity, making its recognition crucial for managing a subset of obese patients.

Conclusions:

Effective recognition and treatment of NES can aid in managing obesity.
While treatment is nascent, SSRIs like sertraline show efficacy; other options like topiramate and phototherapy warrant further investigation.
Future research should include neuroimaging studies to elucidate the underlying pathophysiology of NES.