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Neurophysiologic intervention in deep brain stimulation treatment for movement disorders: a practical framework
Xuguang Liu1, Peter G Bain, Tipu Z Aziz
1The Movement Disorders and Neurostimulation Group, Department of Neurosciences, Charing Cross Hospital, London, UK; The Movement Disorders and Pain Group, Department of Neurosurgery, Radcliffe Infirmary, Oxford, UK.
Neuromodulation : Journal of the International Neuromodulation Society
|December 14, 2011
Summary
Clinical neurophysiology interventions are crucial for deep brain stimulation in movement disorders. This review highlights neurophysiologic techniques used in treating MS tremor, Parkinson
Area of Science:
- Clinical neurophysiology
- Neurosurgery
- Neurology
Background:
- Clinical neurophysiology plays a vital role in perioperative functional neurosurgery.
- Deep brain stimulation (DBS) relies on electrical modulation of brain activity for therapeutic effects, with electrode implantation being a key surgical step.
Purpose of the Study:
- To review neurophysiologic interventions in deep brain stimulation for movement disorders.
- To present evidence from the authors' integrated experience across two UK hospitals.
Main Methods:
- Review of neurophysiologic procedures integrated into functional neurosurgery.
- Analysis of clinical experience in deep brain stimulation for movement disorders.
Main Results:
- Neurophysiologic procedures are integral to neurosurgery.
- Deep brain stimulation's efficacy is linked to electrically modulating brain activity.
Conclusions:
- Neurophysiologic intervention is essential in deep brain stimulation for movement disorders.
- The review covers experiences with multiple sclerosis tremor, Parkinson's disease, and dystonia.

