Peripheral nerve stimulation for unremitting ophthalmic postherpetic neuralgia

Postherpetic neuralgia (PHN) is a common cause of chronic pain in the elderly. Opioids and adjunctive analgesics such as antidepressants and anticonvulsants effectively reduce discomfort in many patients, while others have pain that remains resistant to all forms of therapy. Spinal cord stimulation has shown promise for severe truncal and extremity PHN, but has no impact on neuralgias of cranial nerve origin. Peripheral nerve stimulation has been described for such problems as chronic regional pain syndrome, but to date has not been reported for cranial nerve syndromes. This article describes the cases in which an 86-year-old man and a 76-year-old woman with intractable PHN of greater than 6 and 4 years, respectively, were effectively treated with peripheral nerve stimulation of the ophthalmic division of the trigeminal nerve.