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Updated: May 26, 2026
10:01
Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
ABO-incompatible lung transplantation in an infant
H Grasemann1, M de Perrot, G N Bendiak
1Department of Pediatrics, Transplant Center, Hospital for Sick Children, Toronto, ON, Canada.
Summary
This study reports the first ABO-incompatible infant lung transplant, successfully treating a fatal condition. The infant is thriving, demonstrating the feasibility of ABO-incompatible lung transplants for infants.
Area of Science:
- Pediatric Surgery
- Transplantation Immunology
- Neonatal Care
Background:
- Waitlist mortality remains a significant challenge in solid-organ transplantation.
- Infants with fatal conditions like surfactant protein B deficiency require life-saving interventions.
- Lung transplantation is the only definitive therapy for certain neonatal respiratory failures.
