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Updated: May 26, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
[Renal infarction in two patients with acute abdominal pain]
Marleen S van Brussel1, Cornelis T Grutters, Cornelis A Verburgh
1Kennemer Gasthuis, Haarlem, Afd. Interne geneeskunde, the Netherlands. msvanbrussel@gmail.com
Background:
Renal infarction is a condition not known to every physician, with often non-specific symptoms. The diagnosis is therefore often not considered initially in patients with acute abdominal pain.
Case Descriptions:
In a 77-year-old man a renal infarction was found by chance on a CT-scan performed performed for the evaluation of dyspnoea. Previously he had visited the emergency unit with abdominal pain, in retrospect attributable to renal infarction. A 61-year-old man initially labelled as suffering from gastro-enteritis was diagnosed correctly with renal infarction after his renal function deteriorated and the lactate dehydrogenase (LDH) activity increased.
Conclusion:
A raised serum creatinine level and LDH activity are classic indicators of renal infarction. In addition, most patients have haematuria. Typical wedge-shaped perfusion defects are visible on a CT-scan with intravenous contrast. Timely diagnosis of renal infarction is important both for the prevention of recurrence of thromboembolic complications and for potential revascularisation. The diagnosis of renal infarction should be included in the differential diagnosis in patients with acute abdominal pain.
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