Neonatal surgical reconstruction and peri-operative care for hypoplastic left heart syndrome: current strategies
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Published on: June 16, 2023
Stephanie Fuller1, Nancy Ghanayem, Paul Chai
1Cardiac Surgery, Children's Hospital of Philadelphia, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. FULLERS@email.chop.edu
Insights
Management of hypoplastic left heart syndrome (HLHS) in newborns has improved outcomes over 30 years. This review focuses on current peri-operative and palliative surgical strategies for HLHS.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Surgical Innovation
Background:
- Hypoplastic left heart syndrome (HLHS) is a complex congenital heart defect.
- Significant advancements in management have led to improved survival rates over the past three decades.
Purpose of the Study:
- To review current peri-operative and palliative surgical strategies for HLHS.
- To provide a descriptive overview of evolving treatment approaches.
Main Methods:
- Literature review focusing on descriptive analysis.
- Synthesis of information from multi-centered databases and limited prospective trials.
Main Results:
- Management strategies for HLHS have evolved considerably.
- Outcomes have dramatically improved due to these changes.
Conclusions:
- Current peri-operative and palliative surgical strategies represent the forefront of HLHS management.
- Further research is needed to compare outcomes of different strategies.
Abstract:
The management of newborns with hypoplastic left heart syndrome has changed significantly over the past three decades, with an associated dramatic improvement in outcomes. The aim of this paper is to discuss current peri-operative and palliative surgical strategies. Owing to the fact that comparative outcomes for these strategies have been addressed in a limited number of prospective trials and extractions from multi-centred databases, the primary focus of this review is descriptive.
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