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Influence and critique of CREST and ICSS Trials
Frank J Veith1, Kosmas I Paraskevas
1Division of Vascular Surgery, New York University Medical Center, Bronx, New York 10471, USA. fjvmd@msn.com
Abstract:
The principle findings of the Carotid Revascularization Endarterectomy Versus Stenting Trial and the International Carotid Stenting Study are reviewed and discussed. Flaws and possible weaknesses in both trials are highlighted. The possibility that some Carotid Revascularization Endarterectomy Versus Stenting Trial conclusions have been misinterpreted in ways not justified by the trial's data is considered. This possibility may have prompted one conclusion of a recent American Heart Association Guideline on the management of carotid artery disease to be misleading.
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