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Published on: March 29, 2022
Refractive shift in pseudophakic eyes during the second decade of life
Rupal H Trivedi1, M Edward Wilson, Dipankar Bandyopadhyay
1Miles Center for Pediatric Ophthalmology, Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina 29425-5536, USA. trivedi@musc.edu
Insights
Children
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Refractive Surgery
Background:
- Children undergoing cataract surgery often receive intraocular lens (IOL) implantation.
- Refractive development continues into adolescence, potentially affecting visual outcomes after IOL implantation.
Purpose of the Study:
- To evaluate the refractive shift in pseudophakic eyes of children after their 10th birthday.
Main Methods:
- A case series analyzed refractive data from 114 pseudophakic eyes in children with at least two refractions one year apart after age 10.
- Regression analysis was used to predict postoperative refraction.
Main Results:
- A significant myopic shift occurred in 86.8% of eyes, averaging -0.30 diopters per year.
- Age at IOL implantation did not influence refractive shift, but differences were noted between racial groups.
- Refractive shifts in operated eyes were comparable to fellow eyes in unilateral cases.
Conclusions:
- Children experience continued myopic progression after age 10, impacting IOL selection and multifocal IOL use in adolescents.
- These findings are crucial for optimizing IOL power calculations and managing visual outcomes in pediatric pseudophakic eyes.
Purpose:
To evaluate the refractive shift in pseudophakic eyes of children after their 10th birthday.
Setting:
Storm Eye Institute, Charleston, South Carolina, USA.
Design:
Case series.
Methods:
One eye of each patient with at least 2 refractions at a minimum of a 1-year interval after the 10th birthday was analyzed.
Results:
One hundred fourteen pseudophakic eyes (114 patients) were identified. The mean initial refraction was -0.65 diopter (D) ± 2.27 (SD) and the mean final refraction, -1.78 ± 2.82 D. The mean shift in refraction was -1.13 ± 1.36 D; the mean shift in refraction per year was -0.30 ± 0.38 D. Postoperative refraction could be predicted by regression analysis (P<.001). There was a myopic shift in refraction in 86.8% of eyes; 64.0% of eyes had up to a 0.50 D myopic shift per year. Age at the time of intraocular lens (IOL) implantation (before or after 10 years of age) did not influence the refractive shift in pseudophakic eyes of children after their 10th birthday. However, the refractive shift was significantly different between black patients and white patients (P=.006). In unilateral cases, 27 eyes had refraction data available for the fellow eye. The mean refractive shift per year was -0.19 D in the operated eye and -0.22 D in the fellow eye (P=.67).
Conclusion:
A myopic shift in refraction continued in children after 10 years of age, which has important implications for the use of multifocal IOLs in preteens and teenagers and for IOL power selection.
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