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Preoperative radiation therapy for upper rectal cancer T3,T4/Nx: selectivity essential
Sarah Popek1, Vassiliki Liana Tsikitis, Lisa Hazard
1Department of Surgery, Section of Surgical Oncology, University Medical Center, University of Arizona, Tucson, AZ, USA.
Abstract:
This review explores the current available literature regarding the role of neoadjuvant therapy for upper locally advanced rectal cancers (≥10 cm-15 cm). Although there is a paucity of data evaluating the outcomes of preoperative chemoradiation for upper rectal cancers the authors suggest that T3N0 tumors will not likely benefit from radiation and that treatment of T4N0 should be individualized.
