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Updated: May 26, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Functional imaging of non-motor signs in Parkinson's disease
Bénédicte Ballanger1, Alice Poisson, Emmanuel Broussolle
1CNRS, UMR 5229, Centre de Neurosciences Cognitives, Bron, France.
Abstract:
Non-motor signs encountered in Parkinson's disease consist in a heterogeneous group of manifestations including hyposmia, pain, fatigue, sleep disorders, neuropsychic disorders. Functional imaging techniques provide an invaluable method to understand their pathophysiology, allowing us to study the abnormalities of brain metabolism or perfusion associated with these manifestations or the underlying dysfunction of different neurotransmission systems. The present paper covers the recent advances provided by functional imaging in this area.
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