Related Experiment Video
Updated: May 26, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
A neurocomputational approach to obsessive-compulsive disorder
Tiago V Maia1, James L McClelland
1Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, 1051 Riverside Drive, Unit 78, New York, NY 10032, USA. tmaia@columbia.edu
Abstract:
A recent article shows that a change in a single parameter in a neural-network model of brain dynamics leads to repetitive behaviors that resist termination and towards which the network tends. These findings may have implications for obsessive-compulsive disorder and are consistent with evidence of glutamatergic hyperactivity in this disorder.
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