Related Experiment Video
Updated: May 26, 2026

Polymerase Chain Reaction and Dot-Blot Hybridization for Leptospira Detection in Water Samples
Published on: June 14, 2024
Leptospirosis prevalence in Chinese populations in the last two decades
Chenglin Zhang1, Huan Wang, Jie Yan
1State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital of the School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310058, PR China.
Abstract:
Leptospirosis is a common zoonotic disease in China. From 1991 to 2010, its average annual incidence was 0.70 cases per 100,000 population. During these two decades, three major outbreaks of leptospirosis occurred due to flooding and heavy rainfall. Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai is the predominant leptospire responsible for at least 60% of Chinese cases, and Apodemus agrarius serves as the major animal host. Based on the differences in predominant leptospiral serovars, epidemic features and incidence, there are three leptospirosis-prevalent regions in China. However, the incidence has significantly decreased in the last ten years.
Related Concept Videos
Bacterial Phylum Spirochaetes
Infectious Diseases and Their Occurrence
Single Nucleotide Polymorphisms-SNPs
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health condition at a...
Investigation of Disease Outbreaks
