Related Experiment Video
Updated: May 26, 2026

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
Type D personality, self-efficacy, and medication adherence following an acute coronary syndrome
Gerard J Molloy1, Gemma Randall, Anna Wikman
1Division of Psychology, School of Natural Sciences, Cottrell Bldg, University of Stirling, Stirling FK9 4LA, Scotland. g.j.molloy@stir.ac.uk
Insights
Negative affectivity, a component of Type D personality, is linked to poorer medication adherence in heart disease patients, potentially mediated by lower self-efficacy. This highlights the importance of addressing negative emotions for better treatment outcomes.
Area of Science:
- Cardiology
- Psychology
- Health Behavior
Background:
- Coronary heart disease (CHD) patients often struggle with medication adherence.
- Type D personality, characterized by negative affectivity and social inhibition, is prevalent in CHD populations.
- Self-efficacy plays a crucial role in managing chronic illnesses like CHD.
Purpose of the Study:
- To investigate the relationship between Type D personality, self-efficacy, and medication adherence in CHD patients.
- To determine if self-efficacy mediates the association between Type D personality traits and medication adherence.
Main Methods:
- Prospective observational study of 165 patients hospitalized for acute coronary syndrome.
- Assessment of Type D personality, self-efficacy, and medication adherence at 3 weeks post-hospitalization.
- Follow-up medication adherence measurement at 6 months using self-report; statistical analyses included multiple linear regression and mediation analysis.
Main Results:
- 30% of patients exhibited Type D personality.
- Type D personality was associated with significantly poorer medication adherence at 6 months.
- Negative affectivity, a component of Type D personality, was independently associated with poorer adherence, partly mediated by lower self-efficacy.
Conclusions:
- Negative affectivity, rather than the full Type D construct, appears more critical in predicting medication adherence in CHD.
- Lower self-efficacy may explain the link between higher negative affectivity and reduced medication adherence.
- Interventions targeting negative affectivity and enhancing self-efficacy could improve medication adherence in CHD patients.
Objective:
To assess the relationship among Type D personality, self-efficacy, and medication adherence in patients with coronary heart disease.
Methods:
The study design was prospective and observational. Type D personality, self-efficacy for illness management behaviors, and medication adherence were measured 3 weeks after hospitalization for acute coronary syndrome in 165 patients (mean [standard deviation] age = 61.62 [10.61] years, 16% women). Self-reported medication adherence was measured 6 months later in 118 of these patients. Multiple linear regression and mediation analyses were used to address the study research questions.
Results:
Using the original categorical classification, 30% of patients with acute coronary syndrome were classified as having Type D personality. Categorically defined patients with Type D personality had significantly poorer medication adherence at 6 months (r = -0.29, p < .01). Negative affectivity (NA; r = -0.25, p = .01) and social inhibition (r = -0.19, p = .04), the components of Type D personality, were associated with medication adherence 6 months after discharge in bivariate analyses. There was no evidence for the interaction of NA and social inhibition, that is, Type D personality, in the prediction of medication adherence 6 months after discharge in multivariate analysis. The observed association between NA and medication adherence 6 months after discharge could be partly explained by indirect effects through self-efficacy in mediation analysis (coefficient = -0.012; 95% bias-corrected and accelerated confidence interval = -0.036 to -0.001).
Conclusions:
The present data suggest the primacy of NA over the Type D personality construct in predicting medication adherence. Lower levels of self-efficacy may be a mediator between higher levels of NA and poor adherence to medication in patients with coronary heart disease.
Related Concept Videos
Acute Coronary Syndrome IV: Interprofessional Care
Stress Prevention and Stress Management Techniques I
Conscientiousness
Conscientious individuals tend to be organized, responsible, and disciplined. They prioritize completing tasks and following structured routines,...
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Self-Efficacy
Coronary Artery Disease V: Interprofessional Care