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A Comprehensive Approach to Analyze the Cell Components of Cerebral Blood Clots
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Management of the clotting system: a European perspective

Brigitte E Ickx1, David Faraoni

  • 1Department of Anesthesiology, Hôpital Universitaire Erasme, Brussels, Belgium. brigitte.ickx@erasme.ulb.ac.be

Current Opinion in Anaesthesiology
|December 14, 2011
PubMed

Insights

Managing coagulation in cardiac surgery patients is complex due to aging populations and new antithrombotic drugs. This review covers perioperative treatments and monitoring for bleeding and coagulopathy.

Area of Science:

  • Anesthesiology
  • Cardiovascular Surgery
  • Hematology

Background:

  • Cardiovascular surgery patients are aging and have comorbidities, complicating coagulation management.
  • Pre-existing treatments with anticoagulants and antiplatelet agents are common.
  • Perioperative bleeding and coagulopathy pose significant risks.

Purpose of the Study:

  • To review current knowledge and available treatments for coagulation management in cardiac surgery.
  • To discuss new antithrombotic agents and their preoperative implications.
  • To highlight advancements in bleeding and coagulopathy treatment and monitoring.

Main Methods:

  • Literature review of perioperative coagulation management in cardiovascular surgery.
  • Discussion of new antithrombotic drugs and their clinical use.
  • Overview of hemostatic agents and monitoring devices available in Europe.

Main Results:

  • New antithrombotic drugs increase the complexity of perioperative coagulation management.
  • Various products for treating bleeding and coagulopathy are available in Europe.
  • Novel monitoring devices, particularly for platelet function, are emerging.

Conclusions:

  • Coagulation management in cardiac surgery is increasingly complex due to new pharmacotherapies.
  • Improved and developed monitoring strategies are essential, especially for platelet function assessment.
  • Effective perioperative management requires a comprehensive understanding of new agents and monitoring tools.
Abstract

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