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Updated: May 26, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Primary cutaneous sarcomatoid anaplastic large-cell lymphoma
Katrina Bassett1, Nathalie Stutz, Melissa L Stenstrom
1Department of Dermatology, Medical College of Wisconsin, Milwaukee, USA. katie.bassett@nsd.com
Abstract:
A case of primary cutaneous anaplastic large-cell lymphoma with sarcomatoid histologic features is described. Sarcomatoid anaplastic large-cell lymphoma has previously been reported only ten times in the literature. It is a diagnostic challenge because of sarcomatoid features that include atypical spindle-shaped cells, a storiform architecture, and a mucinous stroma. Clues pointing toward the diagnosis of lymphoma may be very subtle. Awareness of this entity can lead to more accurate recognition of a potentially fatal disease.
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