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Updated: May 26, 2026

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Published on: February 23, 2024
Implementing personalized medicine in a cancer center
David A Fenstermacher1, Robert M Wenham, Dana E Rollison
1Department of Biomedical Informatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA. dfenster@moffitt.org
The Total Cancer Care initiative collects patient data and tumor samples to personalize cancer treatment. This program aims to match the right treatment to the right patient at the right time.
Area of Science:
- Oncology
- Genomics
- Bioinformatics
Background:
- Personalized cancer care requires comprehensive patient data.
- Initiatives are needed to collect and analyze clinical and molecular data.
Purpose of the Study:
- To establish a collaborative program for personalized cancer care.
- To create a robust data infrastructure for cancer research.
Main Methods:
- Partnering with patients, clinicians, industry, academia, and hospitals.
- Developing a formal protocol and patient consent process.
- Constructing an IT platform for data warehousing.
Main Results:
- Over 76,000 cancer patients enrolled.
- Established capabilities and resources for personalized medicine.
- Collected lifetime tumor specimens and clinical data.
Conclusions:
- The Total Cancer Care initiative is foundational for personalized medicine.
- Collaborative efforts are key to advancing precision oncology.
- Data collection and infrastructure are vital for treatment optimization.
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