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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Mutations01:35

Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Mutations01:39

Mutations

Overview
Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

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Detecting Anastasis In Vivo by CaspaseTracker Biosensor
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Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

Preventable exposures associated with human cancers.

Vincent James Cogliano1, Robert Baan, Kurt Straif

  • 1Section of IARC Monographs, International Agency for Research on Cancer, World Health Organization, Lyon, France. imo@iarc.fr

Journal of the National Cancer Institute
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

The International Agency for Research on Cancer (IARC) identified cancer sites linked to over 100 agents. Despite advances, some common cancers still lack identified causes.

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Area of Science:

  • Oncology
  • Carcinogenesis
  • Public Health

Background:

  • Understanding cancer causes is vital for control and research.
  • The International Agency for Research on Cancer (IARC) Monograph series is a key resource for carcinogen classification.
  • Recent IARC reviews provide updated information on carcinogens and associated cancer sites.

Purpose of the Study:

  • To compile and present information on cancer sites linked to over 100 carcinogenic agents.
  • To identify known and suspected causes of cancer for specific anatomical sites.
  • To summarize the scientific rationale, including mechanistic data, for carcinogen classifications.

Main Methods:

  • Leveraging the forthcoming IARC Monographs Volume 100 findings.
  • Listing cancer sites associated with each identified carcinogenic agent.
  • Reorganizing data to present causes of cancer by anatomical site.
  • Summarizing mechanistic data supporting carcinogen classifications.

Main Results:

  • Cataloged cancer sites for over 100 carcinogenic agents.
  • Presented a consolidated list of known and suspected cancer causes by site.
  • Highlighted the increasing use of mechanistic data in carcinogen identification.
  • Noted ongoing epidemiological research identifying new carcinogens and exposure-response relationships.

Conclusions:

  • The current state-of-the-science in carcinogen identification is advanced by IARC's comprehensive review.
  • Mechanistic and epidemiological data are crucial for identifying cancer causes.
  • Despite progress, significant knowledge gaps remain for the etiology of common human cancers.