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[Epilepsy after operation for ruptured intracranial aneurysm].
A Ohkuma1, M Kawaguchi, S Sugimoto
1Department of Neurosurgery, Prefectural Gifu Hospital.
No Shinkei Geka. Neurological Surgery
|August 1, 1990
Summary
Postoperative epilepsy occurred in 23.6% of patients after anterior circulation aneurysm surgery. Key risk factors include multiple aneurysms and severe hemorrhage, guiding anticonvulsant therapy duration.
Area of Science:
- Neurosurgery
- Neurology
- Epileptology
Context:
- Ruptured aneurysms of the anterior circulation require surgical intervention.
- Postoperative epilepsy is a significant complication following such surgeries.
- Anticonvulsant prophylaxis is standard practice.
Purpose:
- To evaluate the incidence of postoperative epilepsy after anterior circulation aneurysm surgery.
- To identify risk factors associated with the development of postoperative epilepsy.
- To provide recommendations for anticonvulsant therapy in these patients.
Summary:
- This study analyzed 55 patients undergoing surgery for ruptured anterior circulation aneurysms.
- The overall incidence of postoperative epilepsy was 23.6%, with a mean latency of 11 months.
- Significant risk factors identified include multiple aneurysms, preoperative severity, subarachnoid hemorrhage, intracerebral hematoma, hydrocephalus, EEG abnormalities, low-density CT lesions, and neurological deficits.
Impact:
- Findings underscore the importance of prophylactic anticonvulsant treatment for all patients.
- Identified risk factors can help personalize treatment duration and intensity.
- Monitoring clinical course, EEG, and drug levels is crucial for effective management.