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Updated: May 26, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Cold urticaria: case series and literature review]
Jorge Mario Sánchez1, Ruth Helena Ramírez, Liliana María Tamayo
1Fundación para el Desarrollo de las Ciencias Médicas y Biológicas (FUNDEMEB), Cartagena, Colombia. jotamsc@yahoo.com
Abstract:
Cold urticaria is one of the five most common causes of chronic urticaria and is grouped as a physical urticaria. It can occur after exposure to cold, either through solid objects, air or liquids. Patients may have symptoms of urticaria, angioedema, respiratory distress and even anaphylaxis when the skin is exposed to a cold environment, such as handling refrigerated objects, swimming in cold water or entering an air-conditioned room. Five cases of cold urticaria are presented, followed by a brief literature review.
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