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Calmitine: a calcium-binding mitochondrial protein specific for fast-twitch muscle fibers
B Lucas-Heron1, N Schmitt, B Ollivier
1Laboratoire de Physiologie--U.E.R. de Médecine, Nantes, France.
Neuroscience Letters
|July 17, 1990
Abstract:
Mitochondrial fractions were isolated from fast-twitch (EDL), slow-twitch (soleus) and heart muscle of normal rat (WKY). Protein separation by electrophoresis and study of calcium-45 binding showed that a specific calcium protein (designated as calmitine) was present in the mitochondria of fast-twitch muscle but practically inexistent in slow-twitch and cardiac muscle. It seems to be related to calcium uptake by an energy-dependent mechanism.