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Updated: May 26, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
Published on: September 6, 2017
[A new human leukocyte antigen class I allele, HLA- B*52:11]
Xiao-feng Li1, Xu Zhang, Kun-lian Zhang
1Liaoning Blood Center, Shenyang, Liaoning, People's Republic of China.
Objective:
To identify and confirm a novel HLA allele.
Methods:
A new human leukocyte antigen class I allele was found during routine HLA genotyping by polymerase chain reaction-sequence specific oligonucleotide probes (PCR-SSOP) and sequencing-based typing (SBT).
Results:
The novel HLA-B*52 allele was identical to B*52:01:01 with an exception of one base substitution at position 583 of exon 3 where a C was changed to T resulting in codon 195 changed from CAC(H) to TAC(Y).
Conclusion:
A new HLA class I allele, B*52:11, is identified, and is named officially by the WHO Nomenclature Committee.
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