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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Surgical Correction for Pediatric Epiblepharon and Trichiasis
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Published on: July 8, 2025

Interventions for involutional lower lid entropion.

Kostas G Boboridis1, Catey Bunce

  • 1Aristotle University of Thessaloniki, Pavlou Mela 16, 54622 Thessaloniki, Greece.

The Cochrane Database of Systematic Reviews
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

A single randomized controlled trial (RCT) found that combining everting sutures with a lateral tarsal strip is more effective for correcting involutional entropion than everting sutures alone. More research is needed to compare surgical techniques.

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Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Geriatric Care

Background:

  • Involutional entropion, a common lower eyelid malposition in the elderly, involves the eyelid margin turning inward against the eyeball.
  • Current treatments are primarily surgical, with non-surgical options for early stages, but their comparative effectiveness is not well-established.

Purpose of the Study:

  • To evaluate interventions for involutional entropion.
  • To determine if any surgical method demonstrates superiority over others for entropion correction.

Main Methods:

  • A comprehensive search of multiple databases (CENTRAL, MEDLINE, EMBASE, mRCT, ClinicalTrials.gov, WHO ICTRP) was conducted.
  • Included were randomized controlled trials (RCTs) comparing surgical methods for involutional lower eyelid entropion in individuals over 60.
  • Study selection and data extraction were performed independently by review authors.

Main Results:

  • One RCT involving 63 participants met the inclusion criteria.
  • The trial compared everting sutures alone versus everting sutures with a lateral tarsal strip.
  • The combined procedure (everting sutures and lateral tarsal strip) showed a significantly higher cure rate for involutional entropion compared to everting sutures alone.

Conclusions:

  • A single RCT suggests that combining horizontal and vertical eyelid tightening (everting sutures and lateral tarsal strip) is highly effective for entropion.
  • While retrospective studies support combined repair, robust evidence from multiple RCTs is needed to guide clinical practice and assess recurrence and complication rates.