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Related Concept Videos

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
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Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

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Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

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Acute Pharyngitis01:30

Acute Pharyngitis

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Tonsillitis II: Management01:26

Tonsillitis II: Management

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Updated: May 26, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Systemic corticosteroids for acute sinusitis.

Roderick P Venekamp1, Matthew J Thompson, Gail Hayward

  • 1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85500, Utrecht, Netherlands, 3508 GA.

The Cochrane Database of Systematic Reviews
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

Systemic corticosteroids, when used with antibiotics, offer short-term relief for acute sinusitis symptoms like facial pain and congestion. However, evidence is limited, and further high-quality trials are needed to confirm efficacy and long-term effects.

Related Experiment Videos

Last Updated: May 26, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

Area of Science:

  • Otolaryngology
  • Pharmacology

Background:

  • Acute sinusitis is a prevalent condition causing significant patient discomfort and impacting daily life.
  • Symptoms include facial pain and nasal congestion, leading to primary care consultations.

Purpose of the Study:

  • To evaluate the effectiveness of systemic corticosteroids in alleviating acute sinusitis symptoms.

Main Methods:

  • A systematic review of randomized controlled trials (RCTs) was conducted.
  • Searches included major databases like CENTRAL, DARE, MEDLINE, and EMBASE.
  • Two reviewers independently assessed trial quality and extracted data.

Main Results:

  • Four RCTs involving 1008 adults were included, demonstrating moderate methodological quality.
  • Oral corticosteroids, as adjunctive therapy with antibiotics, showed improved short-term symptom resolution compared to placebo or NSAIDs.
  • Reported side effects were generally mild, but long-term effects remain unstudied, and potential bias exists.

Conclusions:

  • Systemic corticosteroids appear effective for short-term symptom relief in acute sinusitis when used alongside antibiotics.
  • The current evidence base is limited by potential bias and a lack of long-term data.
  • High-quality trials are recommended to further assess efficacy as both adjuvant and monotherapy.