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Atherosclerosis IV: Nursing Management

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Anxiety: Overview01:18

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Related Experiment Video

Updated: May 26, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Interventions for treating anxiety after stroke.

C Alexia Campbell Burton1, John Holmes, Jenni Murray

  • 1School of Healthcare, University of Leeds, Baines Wing Room 3.35, Leeds, UK, LS2 9JT.

The Cochrane Database of Systematic Reviews
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

Anxiety affects 20% of stroke patients. Pharmaceutical treatments like paroxetine and buspirone show promise in reducing anxiety symptoms in stroke survivors with co-morbid anxiety and depression, but more research is needed.

Related Experiment Videos

Last Updated: May 26, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Trials

Background:

  • Approximately 20% of stroke patients experience anxiety.
  • Anxiety can significantly impact post-stroke recovery and quality of life.

Purpose of the Study:

  • To evaluate the effectiveness of treatments for post-stroke anxiety.
  • To assess treatment impact on quality of life, disability, depression, social participation, mortality, and caregiver burden.

Main Methods:

  • Comprehensive literature search across multiple databases (MEDLINE, EMBASE, PsycINFO, etc.) up to October 2010.
  • Included randomized controlled trials (RCTs) assessing anxiety treatment outcomes in stroke patients.
  • Narrative review conducted due to insufficient quality for meta-analysis.

Main Results:

  • Two trials involving 175 participants with co-morbid anxiety and depression were reviewed.
  • Paroxetine and buspirone demonstrated significant reductions in anxiety symptoms compared to standard care.
  • Adverse events were reported, with paroxetine having a higher incidence than buspirone.

Conclusions:

  • Insufficient evidence exists to guide anxiety treatment post-stroke.
  • Pharmaceuticals like paroxetine and buspirone may reduce anxiety in stroke patients with co-morbid anxiety and depression.
  • Further high-quality, randomized placebo-controlled trials are necessary.