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Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes
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Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes

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Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

Maud de Saint-Jean1, Vanessa Delfosse, Dominique Douguet

  • 1Institut de Pharmacologie Moléculaire et Cellulaire, Université de Nice Sophia-Antipolis and Centre National de la Recherche Scientifique, 06560 Valbonne, France.

The Journal of Cell Biology
|December 14, 2011
PubMed
Summary

Osh4p/Kes1p protein transports sterols and phosphatidylinositol 4-phosphate (PI(4)P) between cellular compartments. This lipid exchange mechanism helps create sterol gradients, linking sterol transport and PI(4)P metabolism.

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