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Updated: May 26, 2026
Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
New polyether triterpenoids from Laurencia viridis and their biological evaluation
Francisco Cen Pacheco1, Janny A Villa-Pulgarin2,3, Faustino Mollinedo2
1University Institute for Bio-Organic Chemistry "Antonio González" (IUBO), University of La Laguna (ULL), Astrofísico Francisco Sánchez 2, La Laguna, Tenerife 38206, Spain.
Abstract:
The red seaweed Laurencia viridis is a rich source of secondary metabolites derived from squalene. New polyethers, such as iubol (2), 22-hydroxy-15(28)- dehydrovenustatriol (3), 1,2-dehydropseudodehydrothyrsiferol (4), and secodehydrothyrsiferol (5) have been isolated and characterized from this alga. The structures were determined through the interpretation of NMR spectroscopic data and the relative configuration was proposed on the basis of NOESY spectrum and biogenetic considerations. All new compounds exhibited significant cytotoxic activity against a panel of cancer cell lines.
