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Related Concept Videos

Sensory Perception: Organization of the Somatosensory System01:11

Sensory Perception: Organization of the Somatosensory System

The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
Somatosensation01:33

Somatosensation

The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

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Related Experiment Video

Updated: May 26, 2026

Assessment of Midline Lingual Point-Pressure Somatosensation Using Von Frey Hair Monofilaments
06:31

Assessment of Midline Lingual Point-Pressure Somatosensation Using Von Frey Hair Monofilaments

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Somatosensory information processing in the aging population.

Zheng Zhang1, Eric M Francisco, Jameson K Holden

  • 1Department of Biomedical Engineering, University of North Carolina Chapel Hill, NC, USA.

Frontiers in Aging Neuroscience
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

Aging does not impair the brain's ability to adapt. Central nervous system (CNS) adaptation metrics remain stable, suggesting preserved cortical plasticity compensates for age-related sensory decline.

Keywords:
adaptationagingplasticitysensorysomatosensorytactile

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Area of Science:

  • Neuroscience
  • Gerontology
  • Sensory Physiology

Background:

  • Skin physiology and sensitivity decline with age.
  • Central nervous system (CNS) mechanisms may preserve sensory processing despite peripheral changes.
  • Age-related changes in CNS function are not fully understood.

Purpose of the Study:

  • To investigate age-related changes in sensory processing and CNS function.
  • To determine if central adaptation metrics are maintained in aging individuals.
  • To explore the relationship between CNS adaptation and cortical plasticity.

Main Methods:

  • Quantitative measurements of processing speed, sensory thresholds, discriminative capacity, and adaptation metrics.
  • Subjects aged 18-70 years were observed.
  • Comparison of adaptation metrics with known CNS compromise conditions.

Main Results:

  • Reaction speed and sensory thresholds showed age-related changes.
  • Discriminative capacity and adaptation metrics remained stable across age groups.
  • Stable adaptation metrics suggest preserved CNS function in aging.

Conclusions:

  • The aging CNS retains the capacity for plastic changes, maintaining adaptation metrics.
  • Cortical plasticity may compensate for age-related peripheral sensory degradation.
  • Objective adaptation metrics could serve as indicators of cerebral cortical health.