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Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
Vaccines01:21

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Development of Immunocompetence01:22

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Vaccine Production01:23

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...

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Related Experiment Video

Updated: May 26, 2026

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
08:52

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice

Published on: February 22, 2019

Vaccination recommendations for Germany.

Miriam Wiese-Posselt1, Christine Tertilt, Fred Zepp

  • 1Robert Koch-Institut, Abteilung für Infektionsepidemiologie, Fachgebiet Impfprävention, Berlin.

Deutsches Arzteblatt International
|December 14, 2011
PubMed
Summary
This summary is machine-generated.

Germany's Standing Vaccination Committee (STIKO) provides free, effective vaccinations against numerous infectious diseases for all citizens. The recommendations cover infants, children, adolescents, and adults, ensuring broad public health protection.

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Area of Science:

  • Public Health
  • Immunology
  • Epidemiology

Background:

  • Vaccination is a key strategy for preventing infectious diseases.
  • The Robert Koch Institute's Standing Vaccination Committee (STIKO) in Germany develops national vaccination recommendations.
  • STIKO aims to prevent the occurrence and spread of infectious diseases within the German population.

Purpose of the Study:

  • To review and present the current vaccination recommendations issued by STIKO.
  • To outline the vaccination schedule for different age groups in Germany.

Main Methods:

  • A selective literature review was conducted.
  • Current STIKO recommendations were analyzed and incorporated.

Main Results:

  • The STIKO vaccination calendar includes recommendations from eight weeks of age for diphtheria, tetanus, pertussis, Haemophilus influenzae type b, hepatitis B, poliomyelitis, and pneumococci.
  • From twelve months, vaccinations against measles, mumps, rubella, varicella, and meningococcus serogroup C are advised.
  • Booster vaccinations and catch-up immunizations are recommended for older children and adolescents.
  • Human papillomavirus vaccination is recommended for girls aged 12-17.
  • Adults require regular tetanus, diphtheria, and one-time pertussis boosters.
  • Vaccination against pneumococci and influenza is recommended for individuals aged 60 and above.

Conclusions:

  • STIKO-recommended vaccinations are universally accessible and free for all German citizens.
  • These vaccinations offer robust protection against a wide range of infectious diseases.