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Updated: May 26, 2026

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution
Published on: August 16, 2012
Image reconstruction of a charge coupled device based optical tomographic instrumentation system for particle sizing
Mariani Idroas1, Ruzairi Abdul Rahim, Robert Garnet Green
1Faculty of Chemical & Natural Resources Engineering, University Teknologi Malaysia, 81310 UTM Skudai, Johor, Malaysia. mariani@fkkksa.utm.my
Abstract:
This research investigates the use of charge coupled device (abbreviated as CCD) linear image sensors in an optical tomographic instrumentation system used for sizing particles. The measurement system, consisting of four CCD linear image sensors are configured around an octagonal shaped flow pipe for a four projections system is explained. The four linear image sensors provide 2,048 pixel imaging with a pixel size of 14 micron × 14 micron, hence constituting a high-resolution system. Image reconstruction for a four-projection optical tomography system is also discussed, where a simple optical model is used to relate attenuation due to variations in optical density, [R], within the measurement section. Expressed in matrix form this represents the forward problem in tomography [S] [R] = [M]. In practice, measurements [M] are used to estimate the optical density distribution by solving the inverse problem [R] = [S](-1)[M]. Direct inversion of the sensitivity matrix, [S], is not possible and two approximations are considered and compared-the transpose and the pseudo inverse sensitivity matrices.
