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Updated: May 26, 2026

Bridging the Bio-Electronic Interface with Biofabrication
Published on: June 6, 2012
Effects of electric potential treatment of a chromium hexacyanoferrate modified biosensor based on PQQ-dependent
Ta-Feng Tseng1, Yang-Li Yang, Yuh-Jiuan Lin
1Biomedical Engineering Department, Chung-Yuan Christian University, No. 200, Zhongbei Rd., Zhongli City, Taoyuan County 32023, Taiwan. g9402502@cycu.edu.tw
Abstract:
A novel potential treatment technique applied to a glucose biosensor that is based on pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase (GDH) and chromium hexacyanoferrate (CrHCF) incorporated into a platinum (Pt) electrode was demonstrated. CrHCF, serving as a mediator, was electrochemically deposited on the Pt electrode as ascertained by CV, SEM, FTIR and XPS measurements. The potential treatment of CrHCF, which converts Fe(II) to Fe(III), enables the glucose detection. The amperometric measurement linearity of the biosensor was up to 20 mM (R = 0.9923), and the detection sensitivity was 199.94 nA/mM per cm(2). More importantly, this biosensor remained stable for >270 days.
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