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A Luciferase-fluorescent Reporter Influenza Virus for Live Imaging and Quantification of Viral Infection
Published on: August 14, 2019
Do people taking flu vaccines need them the most?
1KNG Health Consulting. Rockville, Maryland, United States of America.
Plos One
|December 14, 2011
Summary
The study found a mismatch between flu infection risk and vaccination rates. Targeting vaccines to high-risk groups, including those with low socioeconomic status and families with children, could improve flu vaccine policy effectiveness.
Area of Science:
- Public Health
- Epidemiology
- Vaccinology
Background:
- Effective influenza vaccine strategies aim to vaccinate individuals at highest risk of infection.
- Previous research has not fully explored the link between flu infection risk and vaccination rates.
Purpose of the Study:
- To investigate the relationship between the risk of influenza infection and the likelihood of receiving vaccination.
- To analyze this relationship in both the general population and high-priority groups.
Main Methods:
- Utilized nationally representative US data and multivariate regression models.
- Assessed individual characteristics linked to unvaccinated flu infection risk and vaccination rates.
- Calculated the correlation between infection probability and vaccination probability for distinct population groups.
Main Results:
- The high-priority population exhibited higher vaccination rates than the general population.
- A negative correlation was observed between the risk of infection when unvaccinated and vaccination rates in both populations (r = -0.067, p<0.01).
- This negative association was more pronounced in the high-priority group (r = -0.361, p<0.01).
Conclusions:
- A significant disconnect exists between individuals receiving flu vaccines and those at high risk of infection.
- Vaccine policy could be enhanced by targeting individuals with lower socioeconomic status, unhealthy behaviors, working individuals, and families with children.
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