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[Efficacy of tribendimdine in treatment of hookworm infection]
Li-Guang Tian1, Guo-Jin Cheng, Feng-Feng Wang
1National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Center for Malaria, Schistosomiasis and Filariasis, Key Laboratory of Parasite and Vector Biology, Ministry of Health,Shanghai 200025, China.
Objective:
To study the efficacy of tribendimdine in the treatment of hookworm infection.
Methods:
Forty-seven cases of hookworm infection detected in a cross-sectional study were selected and randomly divided into two groups, one was experimental group (23 cases) treated with tribendimdine and the other was control group (24 cases) treated with albendazole. The negative conversion rates and the incidence rates of adverse effects in the two groups were observed and compared.
Results:
The negative conversion rates and the incidence rates of adverse effects of the two groups were 95.65% and 95.83%, 8.70% and 8.33%, respectively, there were no statistical differences (both P values > 0.05).
Conclusion:
The efficacy of tribendimdine in the treatment of hookworm infection is similar to albendazole.
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