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Updated: May 26, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
Published on: December 15, 2023
[Hepatitis B in clinical practice]
1Leberzentrum Hamburg, IFI Institut für Interdisziplinäre Medizin an der Asklepios Klinik St Georg, Hamburg. petersen@ifi-medizin.de
Abstract:
Approximately 500000 individuals in Germany are chronically infected with hepatitis B of which most have been still not diagnosed or adequately treated. Patients with chronic hepatitis B are at risk to develop advanced liver fibrosis and cirrhosis and subsequently hepatocellular carcinoma. National and international guidelines should be valued as a practical help in the management of these patients. By the end of 2007 a national German hepatitis B guideline has been published, followed by a Clinical Practice Guideline of the European Association for the Study of the Liver (EASL) in 2009. An update of the National German guideline was published in the mid of 2011. The recommendations of these guidelines are delineated. Most importantly the management of hepatitis B remains complicated and needs very experienced hepatologists.
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