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Efficacy of two different CHX-containing desensitizers: a controlled double-blind study
S Drebenstedt1, A Zapf, T Rödig
1Department of Preventive Dentistry, University of Goettingen, Germany. steffi.drebenstedt@med.uni-goettingen.de
Operative Dentistry
|December 15, 2011
Summary
Cervitec Plus (C+) offers a longer-lasting reduction in cervical tooth hypersensitivity compared to Cervitec (C). Both agents effectively reduce sensitivity, but C+ demonstrates sustained benefits up to 90 days, particularly for anterior teeth.
Area of Science:
- Dentistry
- Dental Materials Science
Background:
- Cervical dentin hypersensitivity is a common dental condition.
- Existing treatments like Cervitec (C) aim to alleviate tooth sensitivity.
Purpose of the Study:
- To compare the efficacy and duration of action of Cervitec Plus (C+) against Cervitec (C) for tooth desensitization.
- To evaluate the long-term effects of these agents on cervical dentin hypersensitivity.
Main Methods:
- A monocentric, double-blind, placebo-controlled study involving 120 subjects.
- Random assignment into three groups: Cervitec Plus (C+), Cervitec (C), and placebo (P).
- Application of varnishes and reassessment of pain scores at 1, 7, 30, and 90 days post-application.
Main Results:
- Both Cervitec (C) and Cervitec Plus (C+) significantly reduced hypersensitivity compared to placebo after 30 days (p<0.001).
- After 90 days, C+ maintained significant hypersensitivity reduction (p=0.001), while C did not (p=0.05).
- C+ showed a significant difference for anterior teeth hypersensitivity reduction compared to C at 90 days (p=0.012).
Conclusions:
- Both Cervitec (C) and Cervitec Plus (C+) are effective in reducing cervical tooth hypersensitivity.
- Cervitec Plus (C+) provides a longer duration of action in reducing tooth hypersensitivity, especially for anterior teeth.
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