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Can transthoracic Doppler echocardiography be used to detect coronary slow flow phenomenon?

Shao-Ping Nie1, Li-Li Geng, Xiao Wang

  • 1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China. spnie@126.com

Chinese Medical Journal
|December 15, 2011
PubMed

Insights

Transthoracic Doppler echocardiography (TTDE) shows lower coronary diastolic flow velocities in patients with coronary slow flow phenomenon (CSFP). This non-invasive technique correlates with the corrected thrombolysis in myocardial infarction (CTFC) frame count, suggesting its potential for CSFP monitoring.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Echocardiography

Background:

  • Coronary slow flow phenomenon (CSFP) is an angiographically defined entity.
  • Current diagnostic methods for CSFP lack non-invasive techniques.
  • Accurate diagnosis and monitoring of CSFP are crucial for patient management.

Purpose of the Study:

  • To evaluate the diagnostic and monitoring utility of transthoracic Doppler echocardiography (TTDE).
  • To assess TTDE's ability to detect and quantify coronary slow flow in the left anterior descending (LAD) artery.
  • To correlate TTDE findings with established measures of coronary blood flow.

Main Methods:

  • Twenty-seven patients with LAD CSFP and 38 controls underwent TTDE within 24 hours of coronary angiography.
  • Corrected thrombolysis in myocardial infarction (CTFC) frame count was used to assess coronary flow.
  • Coronary diastolic peak (DPV) and mean (DMV) velocities in the LAD were measured using TTDE.

Main Results:

  • TTDE successfully visualized LAD flow in 92.3% of subjects.
  • Patients with CSFP exhibited significantly lower LAD DPV and DMV compared to controls.
  • A strong inverse correlation was observed between CTFC and both DPV and DMV (r = -0.727 and r = -0.671, respectively).

Conclusions:

  • TTDE can measure coronary diastolic flow velocities in the LAD.
  • Findings suggest an inverse correlation between TTDE-derived velocities and CTFC in CSFP patients.
  • TTDE shows promise for monitoring and evaluating coronary flow in CSFP, warranting further investigation.
Abstract

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