Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Sleepwalking and Sleep Talking01:17

Sleepwalking and Sleep Talking

Somnambulism, commonly known as sleepwalking, involves individuals engaging in activities ranging from simple walking to more complex behaviors such as driving. Sleepwalking typically occurs during the slow-wave sleep stages 3 and 4 early in the night when the person is not dreaming, contradicting the myth that sleepwalkers are acting out their dreams.
Factors that increase the likelihood of sleepwalking include sleep deprivation and alcohol consumption. Contrary to common beliefs, it is safe...
Narcolepsy01:07

Narcolepsy

Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
Nightmares and Night Terrors01:18

Nightmares and Night Terrors

Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares often...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physical health and sleep quality as mediators of the stress-cognitive function pathway in community-dwelling older adults.

International psychogeriatrics·2026
Same author

Circadian rhythm sleep disorders and changes in cognitive function and sleepiness among healthcare workers.

Sleep & breathing = Schlaf & Atmung·2026
Same author

Effects of lemborexant and zolpidem on sleep electroencephalography in older adults with insomnia: a randomized trial.

Sleep advances : a journal of the Sleep Research Society·2026
Same author

Bridging the Educational Gap in Behavioral Sleep Medicine: Enhancing Primary Care Management of Sleep Disorders.

Behavioral sleep medicine·2026
Same author

A data driven approach to assess relationships between sleep, cognition and dementia: Findings from the Sleep and Dementia Consortium.

medRxiv : the preprint server for health sciences·2025
Same author

Decline in Circadian Robustness in Lung Cancer Patients During Immunotherapy is Associated With Increased Risk of Disease Progression and Death.

Journal of biological rhythms·2025

Related Experiment Video

Updated: May 26, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice
08:45

Polygraphic Recording Procedure for Measuring Sleep in Mice

Published on: January 25, 2016

Diagnostic tools for REM sleep behavior disorder.

Ariel B Neikrug1, Sonia Ancoli-Israel

  • 1SDSU/UCSD Joint Doctoral Program in Clinical Psychology, Department of Psychiatry, University of California San Diego, USA.

Sleep Medicine Reviews
|December 16, 2011
PubMed
Summary
This summary is machine-generated.

Diagnosing REM sleep behavior disorder (RBD) involves subjective interviews and objective polysomnography (PSG). Current assessment methods require further validation for definitive diagnosis.

More Related Videos

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Related Experiment Videos

Last Updated: May 26, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice
08:45

Polygraphic Recording Procedure for Measuring Sleep in Mice

Published on: January 25, 2016

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Area of Science:

  • Neurology
  • Sleep Medicine
  • Psychiatry

Background:

  • Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia marked by loss of muscle atonia during REM sleep, leading to motor behaviors.
  • Diagnosis relies on clinical interviews for dream enactment history and polysomnography (PSG) to assess REM sleep without atonia (RWA) and motor activity.

Purpose of the Study:

  • To identify and summarize existing clinical measurements used for assessing RBD.
  • To review the psychometric properties of diagnostic criteria and methods for RBD.

Main Methods:

  • Searched MEDLINE and PsycInfo databases for studies on RBD diagnostic criteria validation.
  • Included studies of adult subjects with sufficient psychometric data for validation.

Main Results:

  • Reviewed 58 studies, encompassing objective measures like electromyographic (EMG) scoring, scintigraphy, actigraphy, and video analysis.
  • Subjective measures included interviews and questionnaires.

Conclusions:

  • Sleep history may suffice for RBD diagnosis in some cases, but PSG is essential for definitive diagnosis.
  • EMG scoring methods lack standardization; further validation is needed for cutoff scores.
  • Questionnaires are useful screening tools but require broader population validation.