Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple sclerosis associated with water intoxication.

D F D'Costa1, P Weston, P A Millac

  • 1Department of Neurology, Leicester Royal Infirmary, UK.

Postgraduate Medical Journal
|August 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Response to: No strong evidence to date for an association between RIMS1 and retinal dystrophy: Mahrood O, et al.

Documenta ophthalmologica. Advances in ophthalmology·2022
Same author

A clinical and electrophysiological case study of a child with a novel frame shift mutation in the CACNA1F and missense variation of RIMS1 genes.

Documenta ophthalmologica. Advances in ophthalmology·2022
Same author

Modelling intestinal glucose absorption in premature infants using continuous glucose monitoring data.

Computer methods and programs in biomedicine·2018
Same author

Autumn Books: Thoroughly modern Oscar.

British medical journal (Clinical research ed.)·2010
Same author

Nocturnal hypoglycaemia in type 1 diabetes--frequency and predictive factors.

QJM : monthly journal of the Association of Physicians·2009
Same author

Transfection of HEK cells via DNA-loaded PLGA and P(FASA) nanospheres.

Journal of drug targeting·2003
Same journal

Comparative efficacy of Janus kinase inhibitors in severe alopecia areata: a network meta-analysis based on randomized controlled trials.

Postgraduate medical journal·2026
Same journal

Two cases of toxic epidermal necrolysis with severe ocular involvement treated with adjunctive tofacitinib.

Postgraduate medical journal·2026
Same journal

Diastolic dysfunction and diabetes: the DIADAD study-a retrospective cohort study from Liverpool.

Postgraduate medical journal·2026
Same journal

Care, cash, and proof: forensic accountability for war-related starvation.

Postgraduate medical journal·2026
Same journal

Response to traumatic injuries in polo players in England.

Postgraduate medical journal·2026
Same journal

Aids to venesection and parenteral drug administration in patients with difficult veins.

Postgraduate medical journal·2026
See all related articles

Multiple sclerosis (MS) exacerbations can trigger syndrome of inappropriate antidiuretic hormone secretion (SIADH). This rare neurological and endocrine association highlights a potential complication in MS patient care.

Area of Science:

  • Neurology
  • Endocrinology
  • Internal Medicine

Background:

  • Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system.
  • Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a condition characterized by excessive water retention.
  • The association between MS exacerbations and SIADH is infrequently reported in medical literature.

Observation:

  • A documented case of multiple sclerosis presented with SIADH.
  • The onset of SIADH occurred subsequent to an exacerbation of the patient's MS.
  • This clinical presentation represents a poorly documented association between the two conditions.

Findings:

  • The study documents a rare instance of SIADH occurring in the context of an MS exacerbation.

Related Experiment Videos

  • This case highlights a potential, though uncommon, complication of MS disease activity.
  • The findings underscore the need for awareness of neuroendocrine disturbances in MS patients.

    • Implications:

    • Clinicians should consider SIADH in the differential diagnosis of MS patients presenting with hyponatremia during exacerbations.
    • Further research may elucidate the pathophysiological mechanisms linking MS activity to SIADH.
    • Recognizing this association can improve diagnostic accuracy and patient management in complex neurological cases.