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Novel picornavirus in domesticated common quail (Coturnix coturnix) in Hungary
Péter Pankovics1, Akos Boros, Gábor Reuter
1Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Szabadság út 7, Pécs 7623, Hungary.
Abstract:
This study reports the detection of a novel picornavirus in domesticated common quail (Coturnix coturnix) in Hungary. The 8159-nucleotide (nt)-long RNA genome of this virus, named quail picornavirus (QPV1-HUN/2010; JN674502), shows only 43%, 39% and 47% amino acid (aa) identity in the P1 (857 aa), P2 (458 aa) and P3 (777 aa) coding regions respectively, to the closest reference, avian sapelovirus. The 5'UTR contains a variant type IV IRES with a 20-nt-long apical "8"-like structure that is conserved in avian-origin and seal picornaviruses. The 390-aa-long L protein is cysteine rich and encodes two copies of a 34-aa-long repeat motif. Quail picornavirus represents a novel picornavirus species and perhaps a novel genus.
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