Declining incidence of candidemia in a tertiary inpatient pediatric population

We examined the incidence of candidemia, Candida species distribution, and antifungal susceptibility patterns in a pediatric institution. We identified 301 episodes of candidemia from 2001 to 2010 inclusive. Annual incidence decreased from 0.68 to 0.12 cases/1,000 patient days between 2004 and 2010. Candida albicans was the most common species, followed by C. parapsilosis. All isolates tested were susceptible to amphotericin B and caspofungin, but 11% were resistant or dose-dependently susceptible to fluconazole.