Related Experiment Video
Updated: May 26, 2026

Isolation of Targeted Hypothalamic Neurons for Studies of Hormonal, Metabolic, and Electrical Regulation
Published on: August 4, 2023
Social regulation of gene expression in the hypothalamic-pituitary-gonadal axis
Karen P Maruska1, Russell D Fernald
1Department of Biology, Stanford University, Stanford, California, USA. maruska@stanford.edu
Abstract:
Reproduction is a critically important event in every animals' life and in all vertebrates is controlled by the brain via the hypothalamic-pituitary-gonadal (HPG) axis. In many species, this axis, and hence reproductive fitness, can be profoundly influenced by the social environment. Here, we review how the reception of information in a social context causes genomic changes at each level of the HPG axis.
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